SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1f116513973b550cfe06e6cd4c35dfbc9a2753d819b39c914f617a60022d978' 
  AND token = 'ZWIb3gox8p61dZDHO6D9SP6UaWOdSKxToIrxFRJha3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}