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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b522e448f7e07370e31dbfd1c5b4c2c4f18e7bb20a50c29e6d67a320f5f914f' 
  AND token = 'gNOixzo/Bf4lsOdYg6J6OdYS/se3QfMYmEhdDr1ROKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}