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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0e32c9e1140cb556b97fd465ff9d3f2c641c01718bbb51862845080d58a4b8b' 
  AND token = 'XjiE1EuRy+I5lVVCeGmpEl0oANiQCbR+VdRZOvwMYG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}