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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b86d260b423c65a4d46264ea23820b4e8fcfb3f70e2fd86f582c909a09a8b6e' 
  AND token = 'c8isZp9pTzF0/QGWnjrVwLqvytgIXtf2xlZ7yO7aYO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}