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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c181d3be33633771d867b56f9d40ff8e6401191f81a9885ef731c2705aec6f66' 
  AND token = 'sRtw7kmxXkagDYE3exBw1T4o0UAVrQ9dUJYS4NPeUCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}