SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def18fea588c5ac2c926cd39cb46046053be0fc6a8cee6f244ddf8f5534df315' 
  AND token = 'eW1FxOq0QGMaGGgLablxIc2v/ZU1jgyzO6YME95QCJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}