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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43416e5be7b293a2fbe7f219661f95cee50af7c741eef3252380298ee5c3c59e' 
  AND token = 'yXL3Dew47O0fXUlhuERP4t3KdOhNRuUxBKlDxSJyDuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}