SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f36586d5746d32d6688067f621a710d0ab3473961650d771bfed6440243a5730' 
  AND token = 'rxTd216n9X14sp8Zrj4nLKA8n285/tBG6gr3MEFnTQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}