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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ab45a8ede7f6f08f25d44426b33c806758bf9a3de333a3a64c5d48c35c0d259' 
  AND token = 'bMyykP1FNa5h52aXHA8I/4BOB8tum2PhLFUNnethk38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}