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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88d894bc3be42d723f9636e4e29ab5a6177f2df1f3e49e6cde3eea327044c39b' 
  AND token = 'xsa0y2L3svDe/1GuQhi4xZ5OnZLD9gsLTHKhvPc5Fs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}