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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6125729946da97393607e62d0af48df04ef3636163a6b11570b676411f1cbd9c' 
  AND token = 'avCdh+KeBf8z8LEQM6djfn+ALxKNhn5iV/lXxEP1ASk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}