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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f8d68dce29039636c281b9eaff7614629f942a02a0a62708210dd86814fc2d4' 
  AND token = 'NWs6pCOOGaPLG/hgKkZhcxw33TK+HsB7dzQXdFxH8ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}