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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e75ad2283f7e060157b3e7db6f3290a1e85d940d198e3b1de48868ce648bd2a' 
  AND token = 'JSpmSwtUHKU/L3xEgF/NmhtHuNwqu0njSfF55kBi90M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}