SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17e307375e1149758016e38e95af2170e0c7e7a6f15c62d0aa827dce0225f8f9' 
  AND token = '/V0TSWHgH+aow8iFC95Dg3RL/YZ7IUtfN2droh5xAoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}