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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04eb25fc65ddc4003c06b25cb83caee9a275302aba3077f7d10a9a983b2fdac4' 
  AND token = 'WuymC+CbEPMbLLRBx92wXFG/ycr+Akmet5RiHZ8RCG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}