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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb7478e95ba8b88bad53e9b9abddc2280bea810432aa45a9f6e6a45ae9b96f10' 
  AND token = 'fuBdoZFFKrgjGKjBYj2x+r1Q5pM4DaQNeASYOHGH/1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}