SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3de217b5936435511ce624fff5ccc5432c4f606a09cc6110ff9909d85b44714' 
  AND token = 'pUFkJ1v+d9QGV1JEXATEgnSR2vDQ8msRNnXNyDPYaCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}