SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0efe738433f12f08f15739e37baeb012535c2a21beaf669cb1700067cc6fced' 
  AND token = 'Dl8Iy3tYHCXydi/g0UwAvpD27w4X9G0jw7H3kyluDxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}