SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbac2645a1e941ca08c49543f59db9b8e185edd67f0453d23c87d048a0163c35' 
  AND token = 'u3ir20/v+0+Hi5noMuR14EarJpUWTurr9X1V3B3Etdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}