SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c0cbfdc389a248fd52923bd6cab73648ba6192630fe07c1c4b03c52d0bd3fd2' 
  AND token = 'zSk+2xqM7lCrMGAn2i6gHnA/7Dj/ECZEh/QDcKT9vSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}