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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '464dd3ff19899a8d7e892ec9e17dd7fc469e578bff85512e4e81e7affbd96d77' 
  AND token = 'bBd4Gw9tdVOWGO8UWC1R6gtoHiqzmFiZxMVlMu677XQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}