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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '314b2f4eded8e4ac5a5681399233e1052c49878ac630017b3d0362e875c4e269' 
  AND token = 'wJG/tHZUj8BtfysDN6XXgsXgm4THwnA2EPzi1FeEYSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}