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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '485ed3b37f6b7aafcc89dd5eed081cdd88e455afbf907c11b5e8e6dd12241542' 
  AND token = 'xQl/xVJKMUD/E2oNRa2W+mB8pGCSg3Tp/NbIWEUNzCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}