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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4accd6474427d02534b99ca73f21a7ae2ef98c95744b4e728315073f0b088af4' 
  AND token = 'SwG2gRbp+mgtrHs+OAH/h194aYybfcHBpMsmj8z2IfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}