SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '375ca0a478d10c9663db7844c642ff3f4fef0006727c4c6c08c827831b301efb' 
  AND token = 'tuHQIXTzOs7Ed4Vvd4HVSRthhRb27tJs6WWMCpr+wdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}