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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '951c6fedc74afb55028a57222e363ba77dfd2be946a4c3640ffc9ada6b272e74' 
  AND token = 'CtTMU9Kkee7gXgghMpTS7+efGlO0ZrZVOQQ3oxrRLb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}