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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7db454e6b49c9fff1457826ae945d983b099c127838634ffe65814adb22f45e7' 
  AND token = 'cyGM0hXo/l4tDw/5C4FUq1/1UKqrmVGoAEJmob2lCf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}