SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b0d4f6d41e840bb73483b1cfeb4d9a7d2a6fdccd1201b714aa36182ec557a87' 
  AND token = 'NFP3tq0IIb4QX1Kqt/T+GReC8UmK83U0ecLfbGzXNKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}