SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e535069da65043681bf50bc2b2da1bd01ad52764b6fe06d87e78eb4b5eb3169f' 
  AND token = 'C2aVyqCuHezIWVh91h8a0p19XRmwhsIbOy23IlnT4KY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}