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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea1b7f1d52b5e140f3d6b0390526b956004d89eb5264959e86afab748fc41eda' 
  AND token = 'daPyuE2WqqVyknUzFEvLti1UPMShO/hfq6QHmuzgnCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}