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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '159ac63c924b2a4f0b286f5e9bd6fae76a4b545c17c75381104631f48acf245e' 
  AND token = 'Rc9CJ9RKMgcdN0PSp6i1UE1VQZ1pesoFbKuwvUvWcVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}