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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2150a0e31ceab773eba76dbd2d2e1b490984a602e26fa84e7e3102206450bdb' 
  AND token = 'HCL9L22dxkBpnrj0A1WfM2x5pghF+Xvi3lsfOlvO6Bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}