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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2208b346611a04b3466d0343bb898091b1c85e54a21a721c8d615f2d3a6a8951' 
  AND token = 'huqrzRCxN4+x5b4O4qCjy5iekSFMKxJuNi1juLpr+b8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}