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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a935e3d22713527d8d86ca660b37f05cddf0fa84302dd9d237a9362dd4c1686' 
  AND token = 'lA7q+TSlbduXVE+qUB0jJ0x8subZ2t+a6Uj0/l2SZpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}