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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eaa4fab3d4157e7a27fa5591cbd31483e405d8fb41cbcdeb17f2f188c486aba' 
  AND token = 'Rxnrly3hoIe6pkpiC6BAY5uzzNMUpwSvOAMvkrJe6Kg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}