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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a54e309389b89ac7730b58a35073d59f32aa79099794523435088e861f9e90' 
  AND token = 'rCOo0Wh3pm5Z0uLvssE5ubyKlSFg76E0cDIrk9Gz1TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}