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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9516da078d4631567e7654a48336b09da5b4e28d1211b2c4eebc17d736699603' 
  AND token = 'EUT/dQ87BWMHh1z2AalEPrc7xQHThvE3ogLhb8SIeK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}