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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7555c19bf0cac6ab2dd2f790a7af11803a4f7e36816622a6012d055dc3edd450' 
  AND token = 'MQdF+vO+Yv2ChVPXfZx+4dM+hmkh74MDDLNwdV1RbDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}