SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee07cd8e63897818baf0ec0a60ab8a4dd23fb227b0d029407f2b97ba48bc5c64' 
  AND token = 's2CsSDtTmD93eBTPDEcvUkpM/zNmADTziverci6i6xE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}