SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452ec1a195e25968d8373f50d7c14a0fa0db1bc499c1324fb54a993fc84a5e17' 
  AND token = 'n4kPKQVTFxwS4s9y8Syn2LBn/t8QsOYVBspRZpf8OG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}