SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6d8d52657f064b7a9243b01f09fb0b7fc63339f467e7272213d88834f474d9d' 
  AND token = 'V4F6c3utfTZGXusw8KeAUct3bHa97r7oqahFlEfBUuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}