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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f13d52528cd6d5a3df8a1466a4bc2405a71bee0bca5ba80a2ceb9e895a3cd00a' 
  AND token = '8OBmb3+FKGwTTKASEsmes7N76+1MKEJJaN5zj+3UFhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}