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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2db2f4e548ff55006f2c4e01c7b18c2b3c4d18635120ad44baffe4142123b718' 
  AND token = 'Ou+SShOBG1m9vn3UjEtuwpLD+zVRlMcCvJ8niFSoutc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}