SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b1c04be06f242b8c2d51be21e2e56f58486703a3b1ef8a626160bc4f1b41aa0' 
  AND token = 'sBFuIwbzedhdD4UTh8ccIZk7rYyVDI/N79ZXiDxUGfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}