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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e34ae3ccaf1163b3d15b96c1c66e164413273fef392f63427e2fbb4275a42b5' 
  AND token = 'OGKY2l/VSHHJoxyN0UaWftyN0+hRdHhNYimKzHwtQC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}