SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06d25b8332af2d7de9fd14d0d19b36f3f7d40e09bbdd7b017aae06a5baaaa571' 
  AND token = 'D0py0u7BGsrDp8A5fxELHramvVRloIYDUhWKbHlUr6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}