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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '398a4c70396f5a600793230bc48f0b2b0cbc7a35b68f107456550711ff64d5a1' 
  AND token = 'YtpoVPlzdiO1uw60TIX276NSJTI/9nPXGAAWjprV/Lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}