SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43279c764bf3add77a5de24e163ed31528d02d7be855abf587b93f7b99fc6488' 
  AND token = 'lllWWVUaOepbkYDBn5RFi3JVfNYyd+BQraSVxYp2FkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}