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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db4b084075ad43e9db3bee27d762777ac2aef509443c47484c0ce098aed1a635' 
  AND token = '2xP/1QbuaI62wjHpNVGPsTJ1plpiYJ8zMm9+inMTTTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}