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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc67886a0e8a3c09da5d668ea448cc0373b19df0597e2dcbafd28c0a6d3b9a14' 
  AND token = 'Fpu+y4Ebrl5biLMRT4UTMPDLDcN/SPs0VjVZm/wJ09I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}